Here are the details on main ingredients in curbing the menace of Advanced Glycosylation Endproducts.

Benfotiamine

Benfotiamine (S-benzyolthiamine-O-monophosphate) is a lipid soluble,
biologically active form of thiamin (vitamin B-1). It belongs to the
family of compounds known as allithiamines, which are found in crushed
garlic. Benfotiamine raises the levels of thiamin pyrophosphate (TPP)
which is the co-enzymated form of thiamin and also stimulates
transkotelase an enzyme responsible for maintenance of normal glucose
metabolic pathways. The activation of the enzyme transketolase, turns
triosephosphates which are glucose-derived compounds into chemicals
that are harmless. Thiamin activates it at level around 20%, which
isn’t enough to stop the glucose-derived compounds accumulating in
healthy cells where as Benfotiamine increases the levels of
transketolase by 300%! Benfotiamine prevents nerve and blood-vessel
damage caused by a build-up of sugar in the tissues. Benfotiamine
helps maintain integrity and health of cells in the presence of blood
glucose and controls formation of Advanced Glycation End products
(AGEs).

Vitacost’s NSI, Source Naturals carry Benfotiamine.

Pyridoxamine

Pyridoxamine is one of the three naturally occurring vitamin B6’s along
with pyridoxal and pyridoxine. Pyridoxamine is a potent natural
substance to inhibit glycosylation. In animal models, pyridoxamine has
inhibited development and progression of diabetic nephropathy and
kidney disorders for both Type 1 and Type 2 diabetes. Pyridoxamine is
also useful in addressing Advanced Lipoxidation Endproducts (ALE’s)
which is thought to be a precursor to atherosclerosis.

Jarrow Formulas produces Pyridoxamine product under the name Pyridoxall.

L-Carnosine

Carnosine is a combination of the amino acids beta-alanine and l-histidine. Carnosine is an important protector against bad side effects of the very things that life depends on such as oxygen, glucose, lipids, protein, trace metals. It protects the proteins of the body by acting as an antioxidant, anti-glycating, metal chelating agent. Carnosine’s structure is supposed to resemble glycation sites on proteins, there by accepting the damage and disposing off the damaging glycation end products.

Vitacost’s NSI, Jarrow Formulas, GNC, Source Naturals carry L-Carnosine.

Acetyl-L-Carnitine

Acetyl-L-Carnitine is the biologically active form of L-Carnitine and readily crosses blood brain barrier. Acetyl-L-Carnitine has been shown in animal models to suppress glycation and reduce advanced glycation end products.

Swanson, Jarrows Formulas, Vitacost’s NSI, Source Naturals, GNC, Vitaminshoppe carry Acetyl-L-Carnitine.